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PUBLICATION DATE
April 25, 2024
Towards More Tolerable Subcutaneous Administration: Review of Contributing Factors for Improving Combination Product Design
Manuscript Objectives:
Subject Matter Experts from the Subcutaneous Drug Development & Delivery Consortium review known attributes that contribute to pain / discomfort upon SC injection, including:
- device and delivery factors that cause physical pain
- formulation factors that trigger pain responses, and
- human factors impacting pain perception
AUTHORS
Neil Mathias, Sylvain Huille, Marie Picci, Robert P. Mahoney, Ronald J. Pettis, Brian Case, Bernhard Helk, David Kang, Ronak Shah, Junchi Ma, Deep Bhattacharya, Yogita Krishnamachari, Dany Doucet, Nathalie Maksimovikj, Sahab Babaee, Patrick Garidel, Reza Esfandiary, Rajesh Gandhi
PUBLICATION
ScienceDirect
© 2025 Subcutaneous Drug Development & Delivery Consortium
English